Experimental evidence in the last decades show that iron is a fundamental element for normal development of the immune system. Its deficiency affects the capacity to have an adequate immune response. The role of iron in immunity is necessary for immune cells proliferation and maturation , particularly lymphocytes, associated with the generation of a specific response to infection. The body has the capacity to reduce the iron availability to be consumed by infectious elements by proteins such as transferrin and lactoferrin. Also, iron is essential for the proliferation of bacteria, parasites, and neoplastic cells .
Thus excess iron could potentially facilitate the development of infections and the invasion of tumoral cells. The immune system has bacteriostatic mechanisms that reduce the availability of the metal, interfering with bacterial growth. Additionally the system uses iron as the intermediary in the production of bacteriostatic cells. The influence of iron on immune function has been long appreciated . However, the molecular basis for this interaction is less well understood. Recently, there have been several important advances that have shed light on the mechanisms that regulate mammalian iron metabolism. The new insights provide a conceptual framework for understanding and manipulating the cross-talk between iron homeostasis and the immune system.
It is clear from the both iron deficiency and iron excess can influence the functioning of the innate and adaptive arms of the immune system . Iron can also have direct effects on the growth and virulence of microbial pathogens . Indeed , an important component of innate anti-microbial defense is based on depriving pathogens of this nutrient . Changes in iron status can thus affect the immune response in multiple ways, particularly in the context of infection, an idea that is worth remembering when considering the value of iron supplementation in areas of the world where infections such as malaria and tuberculosis are highly prevalent. Conversely , chronic immune activation can lead to alterations in iron homeostasis that may impair erythropoiesis and contribute to immunopathology .
Iron supplements help you achieve your daily iron needs to support your immune system . Active Iron works in tune with your body, it targets the natural site of absorption and delivers the right amount of iron, all while helping to reduce gut irritation from iron .
” SUPPLEMENT Facts fefol Immune ”
” Nutritional Information Amount per capsule “
Vitamin D3 (as Cholecalciferol) 500 IU
Vitamin E (as DL-Alpha Tocopheryl Acetate) 4 mg
Vitamin C (as Ascorbic Acid) 70 mg
Vitamin B1 (as Thiamine) 3 mg
Vitamin B2 (as Riboflavin) 2 mg
Vitamin B3 (as Niacin) 20 mg
Vitamin B6 (as Pyridoxine HCl) 10 mg
Folic acid 400 mcg
Vitamin B12 (as Cyanocobalamin) 6 mcg
Vitamin K 50 mg
Iron (as ferrous fumarate) 18 mg
Selenium (selenium selenite) 40 mcg
Magnesium (as magnesium phosphate) 150 mg
Zinc (ZINC OXIDE) 15 mg
Iodine (as potassium iodide) 200 mcg
Pantothenic Acid (as D-calcium pantothenate) 6 mg
Natural mixed carotenoids 2 mg
Biotin 200 mcg
Copper (as copper sulfate) 1 mg
Vitamin D3 :
Essential for baby’s skeletal development and improves calcium absorption and independently provides bone mineral support functions.
Vitamin E :
Helps protecting the cells from oxidative stress.
Vitamin C :
Supports normal function of the Immune system.
B1, B2, Biotin :
Contribute to maintaining normal energy-yielding metabolism & normal functioning of the nervous system.
Niacin , B6 , B3 , B12 , pantothenic acid :
Helps to reduce tiredness and fatigues .
Adequate folic acid n healthful diets may reduce a woman’s risk ET having a child with a neural tune defect, Supplementation should begin before conception as neural tube is formed by day 28 of gestation .
Plays a key role in helping the blood clot, preventing excessive bleeding.
During pregnancy, women’s iron needs go up to support increased blood volume and red blood cell formation, and healthy growth of baby Low levels have been associated with increased risk of low birth weight. Preterm de delivery and other adverse outcomes.
Selenium (selenium selenite)
Selenium necessary for the functioning of the glutathione-peroxidase enzyme system that protects cellular structures from oxidative damage.
Magnesium (magnesium oxide):
Magnesium contributes to normal muscle function. Magnesium contributes to normal muscle function and to normal functioning of the nervous system. Magnesium regulates the interaction of muscles and nerves and therefore ensures the smooth functioning of the entire muscular system. As part of more than 600 enzymes it plays a key-role in energy metabolism. A sufficient provision with magnesium also contributes to the reduction of tiredness and fatigue and maintains a normal psychological.
Zinc (ZINC OXIDE) :
Zinc is involved in many functions of human health including enzymatic; cell differentiation; protein, lipid, and carbohydrate metabolism; gene transcription; and immunity. Zinc deficiency is associated with growth failure and increased susceptibility to infection and skin inflammation, diarrhea, alopecia, and behavioral disturbances.
Important for normal thyroid function in mother and bran development in baby. Consuming processed foods and using non-iodized salt has led to a decrease in dietary intake in women of childbearing age.
Natural mixed carotenoids
Carotenoids are beneficial antioxidants that can protect you from disease and enhance your immune system. provitamin A carotenoids can be converted into vitamin A, which is essential for growth, immune system function, and eye health.
It uses copper to form red blood cells, bone, connective tissue and some important enzymes. Copper is also involved in the processing of cholesterols, the proper functioning of your immune system and the growth and development of babies in the womb .
WARNING : If you are under the care of, or receiving medicines from your doctor, consult your doctor before taking “Fefol Gyne“.
Keep this product out of reach of children .
Iron and Infants
A fetus depends upon nutrients from the mother in order to develop properly. Beginning at conception and ending at birth, the human fetus experiences exponential growth at impossibly quick rates. In order to support rapid growth and development, the human body requires large amounts of vitamins and minerals, particularly the mineral iron. However, many of us do not fully understand the importance of iron in our bodies. Just as iron is used in architecture and manufacturing, it is also an essential building block within our bodies and without it we would not be able to survive and thrive.
As bone marrow develops, it produces red blood cells. Red blood cells contain hemoglobin, the main component of which is iron. Hemoglobin is the substance which collects oxygen from the lungs. As the red blood cells travel through the blood stream, they supply the body with the oxygen and energy needed for completing everyday functions and tasks.
Maternal iron deficiency at pre and post conception has been shown to lead to developmental problems in the fetus. The first and second trimesters are crucial stages for the fetal brain and neurological development
Perinatal iron deficiency adversely affects the growth and functioning of multiple organ systems , including :
- The heart
- Skeletal muscle
- The gastrointestinal tract
- The brain
Iron is essential for neurotransmission, energy metabolism and myelination in the developing brain
The most significant adverse effects of perinatal iron deficiency are neurodevelopmental impairments and predisposition to earlier onset of postnatal iron deficiency. Some studies have shown that iron deficiency between 6 and 24 months of age is associated with long term motor and cognitive development problems that may not all be reversed in spite of subsequent iron supplementation. As infants and toddlers, it is highly recommended that an iron enriched diet is ingested.
Without proper iron levels , children under five will suffer symptoms of deficiency , including :
- Bone pain
- Lack of focus
- Inability to think quickly
- Loss of appetite
Toddlers who develop iron deficient anemia may have insufficient bone development, leading to slow growth. The skin of the mouth and gums will become pale or even slightly